There were on average 84 flights daily making the short hop which takes about an hour, according to the study by air travel intelligence firm OAG.
A large number of airlines serve the route, from full-service carriers such as Singapore Airlines and Malaysia Airlines to budget ones like AirAsia.
A high-speed railway line is being built to link the cities and is expected to be completed in 2026, cutting travel time overland to 90 minutes from around five hours.
Asia dominated the list of the world's 20 busiest international air routes, with 14 operating to and from destinations in the region, Britain-based OAG said.
Two operate within Europe, two in North America, one between North America and Europe, while another is in the Middle East, it added.
The world's second busiest air route is between Hong Kong and the Taiwanese capital Taipei, with 28,887 flights in the year to February, followed by the Jakarta to Singapore route with 27,304 flights.
Published : May 04, 2018
By : Agence France-Presse Singapore