The southern Eindhoven international airport has been closed since noon (1100 GMT), with some 27 inbound flights re-routed and at least six other flights cancelled, according to the airport's website.
The same number of departing flights have been cancelled, affecting between 6,500 to 8,000 passengers, a local news report said.
Meanwhile, Amsterdam's Schiphol airport had to cancel around 100 flights, the NOS public broadcaster reported.
"Take-off and landing capabilities have been reduced by half," the NOS said.
The country's flagship carrier KLM normally operates some 65 flights per hour, but during the heaviest foggy period, only 17 flights could land or take off.
It was not clear when the fog was expected to lift but the Royal Dutch Meteorological Institute has issued a "code yellow" warning in most of the country's central and southern regions until at least midnight (2300 GMT).
Published : December 16, 2018
By : Agence France-Presse The Hague