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Aspirin reduces risk from some cancers, says study

PARIS - Daily, long-term doses of aspirin can slash the risk of cancer of the digestive tract, according to an overview of research published on Wednesday.

Aspirin greatly reduces the risk of developing and dying from bowel, stomach and oesophageal cancer, its authors said.

They found that taking aspirin for 10 years could cut bowel cancer cases by around 35 per cent and deaths by 40 per cent.

Rates of oesophageal and stomach cancers were cut by 30 per cent and deaths from these cancers by 35-50 per cent.

To gain these benefits meant people had to start taking a daily dose of 75-100 mg for at least five years and probably 10 years between the ages of 50 and 65.

No benefit was seen while they took aspirin for the first three years, and death rates were only reduced after five years.

Aspirin has long been considered to be a boost in the fight against cardiovascular disease and has also been investigated for reputed anti-cancer effects.

This is the first to throw up broad evidence that it can be a shield against these types of cancer, the scientists said.

The study, published in the European cancer journal Annals of Oncology, was led by Jack Cuzick, a professor at the the Centre for Cancer Prevention at Queen Mary University of London.

It looked at more than 200 clinical trials and other studies that explored aspirin’s anti-cancer effects.

"Our study shows that if everyone aged between 50-65 started taking aspirin daily for at least 10 years, there would be a nine-per cent reduction in the number of cancers, strokes and heart attacks overall in men and around seven per cent in women," Cuzick said in a press release.

"The total number of deaths from any cause would also be lower, by about four per cent over a 20-year period. The benefits of aspirin use would be most visible in the reduction in deaths due to cancer."

The research said there was a downside to taking daily doses of aspirin -- potential side-effects such as peptic ulcers and bleeding in the digestive tract. In a very small number of elderly people, the bleeding could be life-threatening.

AFP


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