
Scholes has a suspected medial ligament injury and could be out for up to two months, while United are waiting on the extent of Rooney's ankle problem.
"It's difficult to say how serious (Scholes's injury) is but it looks like the medial ligament, in which case it will be six to eight weeks," United manager Sir Alex Ferguson said.
Rooney left the field with an ankle injury, having scored the opener in the Champions League holders' 3-0 win over AaB Aalborg.
"We are hoping it isn't ligament trouble," Ferguson said.
"He just felt his ankle. I would imagine he would be doubtful for the Blackburn game on Saturday."
DPA